MOTS-c (10mg)

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MOTS-c is a mitochondrial-derived peptide composed of 16 amino acids, encoded by the 12S rRNA region of the mitochondrial genome. It plays significant roles in metabolic homeostasis, nuclear gene expression, and has potential therapeutic applications for metabolic dysfunction, insulin sensitivity and age-related diseases.

MOTS-c (10mg) Description

MOTS-c (10mg) (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide discovered in 2015 that functions as a mitochondrial-encoded regulatory signal. The 16-amino acid peptide is encoded by the mitochondrial genome within the 12S rRNA gene and represents an important link between mitochondrial function and metabolism. MOTS-c (10mg) primarily targets skeletal muscle and acts as a metabolic regulator by activating the AMPK (AMP-activated protein kinase) pathway, which is crucial for cellular energy homeostasis.

MOTS-c (10mg) Peptide Information

Property Value
Peptide Sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular Formula C101H152N28O22S2
Molecular Weight 2174.6 g/mol
CAS Number 1627580-64-6
PubChem CID 255386757
Synonyms 1627580-64-6, UNII-A5CV6JFB78, MOTS-c (human) (trifluoroacetate salt), A5CV6JFB78

Product Usage: 

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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